Gunagratinib

立即咨询

Gunagratinib

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2211082-53-8

ICP-192

Gunagratinib (ICP-192) 是一种低毒、具有口服活性的pan-FGFR(成纤维细胞生长因子受体) 抑制剂，可通过共价结合有效、选择性地不可逆地抑制FGFR活性。Gunagratinib 可用于癌症研究。

生物活性

Gunagratinib (ICP-192) is a low toxicity and orally activepan-FGFR(fibroblast growth factor receptors) inhibitor that potently and selectively inhibitsFGFRactivities irreversibly by covalent binding. Gunagratinib can be used for the research ofcancer^[1].

IC₅₀& Target^[1]

FGFR

体外研究
(In Vitro)

Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding^[1].

Clinical Trial

分子量

423.47

性状

Solid

Formula

C₂₂H₂₅N₅O₄

CAS 号

2211082-53-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)