Doxofylline 是一种口服有效的 PDE IV 抑制剂和 A1AR 拮抗剂。
| Cas No. | 69975-86-6 |
| 别名 | 多索茶碱 |
| 化学名 | 7-(1,3-dioxolan-2-ylmethyl)-1,3-dimethylpurine-2,6-dione |
| Canonical SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC3OCCO3 |
| 分子式 | C11H14N4O4 |
| 分子量 | 266.25 |
| 溶解度 | ≥ 11.4mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Doxofylline is an antagonist of adenosine A1 receptor which also inhibits phosphodiesterase IV. References:
[1]. Shukla D, et al. Doxofylline: a promising methylxanthine derivative for the treatment of asthma and chronic obstructive pulmonary disease. Expert Opin Pharmacother. 2009 Oct;10(14):2343-56. |
